Endocrine Abstracts

We report the case of a 34-year-old woman with a personal history of type 1 diabetes mellitus (DM1) since she was 9 years old. Very poor chronic metabolic control stands out despite multiple insulin schemes with multiple complications: nephropathy, retinopathy and peripheral neuropathy. She was admitted to the hospitalization floor due to diabetic ketoacidosis. At admission Hba1c of 15.3%. During admission after treatment with IV insulin, improvement in glycemic control. Nine ...

Introduction: Patients with large non-functioning pituitary macroadenomas often have symptoms due to varying degree of hypopituitarism and/or mass effect on visual structures, while presentation with hydrocephalus is extremely uncommon.Case report: We describe an 82-year-old man who was referred to the Neurology department of our hospital because of rapidly progressive memory loss. The patient was in good health until ten weeks earlier, when he insidious...

Aims: To study if BRAF V600E mutation in thyroid fine needle aspiration (FNA) is associated with specific ultrasound (US) characteristics.Patients and methods: From 2010 to 2014 we reviewed patients with thyroid nodules with the following inclusion criteria: US guided FNA of the nodule and molecular testing for BRAF V600E on the FNA. BRAF mutation was detected using fluorescence melting curve. An expert on US, blinded to the BRAF status reviewed US exami...

Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder characterized by varied neurological symptoms. There are two leading theories regarding the pathophysiology: hypertension crisis and endothelial dysfunction.Case reportWe report the case of a 42-year-old patient with history of hypertension. She presented to the emergency department with headache and bilateral loss of vision. She described one previous e...

Introduction: Ipilimumab is a monoclonal antibody against the inhibitory CTLA-4 receptor expressed on T cells. It provokes an upregulation of the immune system. It is known to cause neuroendocrine disorders, such as hypophysitis, hyppothyroidism/thyroiditis and adrenal insufficiency. Althought it is stipulated that thyroid.stimulating hormone (TSH) levels should be evaluated before administration of each dose of ipilimumab as a screen for thyroid diyfunction, there is no reque...

Introduction: Adrenal crisis is a life-threatening emergency, however, the relation between adrenal crisis and life-threatening arrhythmia is not known. We describe the case of a patient with adrenal crisis and arrhythmia with prolongation of QT interval.Case report: A 56-year-old woman was admitted to our hospital because of syncope. She reported having had similar episodes in the last year. She had no previous diagnoses and was not receiving any treatm...